Description

1-(3-(6-Fluoropyridin-2-Yl)Phenyl)Ethanone is a high-purity fluorinated aromatic ketone building block, identified by CAS number 1245642-55-0. This compound is a critical intermediate for synthesizing advanced pharmaceutical and agrochemical active ingredients, offering a unique structural motif for drug discovery and material science. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector to create novel molecules with enhanced biological activity and selectivity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug candidates.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for improved metabolic stability and bioavailability.
• Material Science Precursor: Used in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its rigid, conjugated structure.
• Chemical Biology Probes: Employed in the design of molecular probes and fluorescent tags for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	1-(3-(6-Fluoropyridin-2-Yl)Phenyl)Ethanone
CAS No.	1245642-55-0
Molecular Formula	C13H10FNO
Molecular Weight	215.22 g/mol
Synonyms	1-[3-(6-Fluoropyridin-2-yl)phenyl]ethanone; 2',6'-Difluoroacetophenone (contextual); 3-(6-Fluoropyridin-2-yl)acetophenone; 3-Acetyl-6-fluorobiphenyl-2-ylamine precursor; 6-Fluoro-2-(3-acetylphenyl)pyridine; Ethanone, 1-[3-(6-fluoro-2-pyridinyl)phenyl]-; (3-(6-Fluoropyridin-2-yl)phenyl)methanone derivative
EINECS	Contact for details

Quality Control

Our production of 1-(3-(6-Fluoropyridin-2-Yl)Phenyl)Ethanone adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically >97% by HPLC), identity confirmation, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and bases. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.