Description

(5-Chloropyrazin-2-Yl)(Pyrrolidin-1-Yl)Methanone is a high-purity, heterocyclic organic building block featuring a chloropyrazine core linked to a pyrrolidine amide. This compound matters as a critical synthetic intermediate for medicinal chemistry research and pharmaceutical development, enabling the creation of novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its versatile chloropyrazine moiety.
• Agrochemical Synthesis: Employed in the development of novel herbicides, fungicides, and insecticides that utilize heterocyclic scaffolds.
• Chemical Biology Probes: Acts as a precursor for synthesizing molecular probes to study biological pathways and enzyme functions.
• Material Science Research: Investigated as a monomer or precursor for advanced organic materials and functional polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized heterocycles.

Basic Information

Product Name	(5-Chloropyrazin-2-Yl)(Pyrrolidin-1-Yl)Methanone
CAS No.	1245215-68-2
Molecular Formula	C9H10ClN3O
Molecular Weight	211.65 g/mol
Synonyms	1-(5-Chloropyrazin-2-yl)pyrrolidin-1-one; (5-Chloro-2-pyrazinyl)(1-pyrrolidinyl)methanone; 5-Chloro-2-(1-pyrrolidinylcarbonyl)pyrazine; 5-Chloro-N-(pyrrolidin-1-yl)pyrazine-2-carboxamide; 1245215-68-2; 5-Chloro-2-pyrrolidin-1-ylcarbonylpyrazine
EINECS	Contact for details

Quality Control

Our (5-Chloropyrazin-2-Yl)(Pyrrolidin-1-Yl)Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.