Description

1-(5-Nitro-2-Pyridinyl)-4-Piperidinecarbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining pyridine and piperidine motifs. This compound is of significant value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries engaged in drug discovery, process development, and the production of specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of new drug candidates, especially for central nervous system (CNS) and anti-infective targets.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its nitro-pyridine functionality.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for constructing more complex heterocyclic compounds in medicinal chemistry.
• Academic & R&D Laboratories: Employed in fundamental chemical research and method development for organic synthesis.
• Contract Manufacturing (CMO): Supplied to CMOs for the production of custom APIs and specialty chemicals under cGMP conditions.

Basic Information

Item	Detail
Product Name	1-(5-Nitro-2-Pyridinyl)-4-Piperidinecarbonitrile
CAS No.	1244642-17-8
Molecular Formula	C11H12N4O2
Molecular Weight	232.24 g/mol
Synonyms	4-Piperidinecarbonitrile, 1-(5-nitro-2-pyridinyl)-; 1-(5-Nitropyridin-2-yl)piperidine-4-carbonitrile; 2-(4-Cyanopiperidin-1-yl)-5-nitropyridine; 5-Nitro-2-(4-cyanopiperidin-1-yl)pyridine; 1244642-17-8; UNII-8J9V6X8F6M; 8J9V6X8F6M
EINECS	Contact for details

Quality Control

Every batch of 1-(5-Nitro-2-Pyridinyl)-4-Piperidinecarbonitrile is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and commercial projects requiring compliance with ICH guidelines and can supply material suitable for use under cGMP conditions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.