Description

5-Bromo-n-(1-Ethylpiperidin-3-Yl)Pyridine-3-Sulfonamide is a high-purity, advanced pharmaceutical intermediate with the CAS number 1244060-04-5. This compound is a critical building block in modern medicinal chemistry, valued for its unique sulfonamide-piperidine-pyridine hybrid structure which enables the synthesis of targeted bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in the fields of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small-molecule drug candidates targeting specific protein receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new chemical entities.
• Kinase Inhibitor Development: Serves as a core scaffold for the design and synthesis of potential kinase inhibitors for cancer therapy.
• CNS Drug Discovery: Employed in the research of compounds targeting neurological pathways due to its piperidine moiety.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological processes and target validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	5-Bromo-n-(1-Ethylpiperidin-3-Yl)Pyridine-3-Sulfonamide
CAS No.	1244060-04-5
Molecular Formula	C12H18BrN3O2S
Molecular Weight	348.26 g/mol
Synonyms	5-Bromo-N-(1-ethyl-3-piperidinyl)-3-pyridinesulfonamide; 3-Pyridinesulfonamide, 5-bromo-N-(1-ethyl-3-piperidinyl)-; 5-Bromo-N-(1-ethylpiperidin-3-yl)pyridine-3-sulfonamide; 1244060-04-5; 5-Br-NEPPS; 5-Bromo-3-pyridylsulfonamide derivative; 1-Ethyl-3-((5-bromopyridin-3-yl)sulfonamido)piperidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-n-(1-Ethylpiperidin-3-Yl)Pyridine-3-Sulfonamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.