Description

tert-Butyl 5-Bromopyridin-3-Ylmethylcarbamate is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in modern organic synthesis, enabling the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up production.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug molecules, particularly those targeting neurological disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its functionalized pyridine core.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and contract research organizations (CROs/CMOs).
• Academic & Industrial R&D: Essential for exploratory chemistry in both academic laboratories and industrial R&D departments focused on heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl 5-Bromopyridin-3-Ylmethylcarbamate
CAS No.	1243698-95-4
Molecular Formula	C11H15BrN2O2
Molecular Weight	287.15 g/mol
Synonyms	5-Bromo-3-(((tert-butoxycarbonyl)amino)methyl)pyridine; tert-Butyl N-[(5-bromopyridin-3-yl)methyl]carbamate; 3-(((tert-Butoxycarbonyl)amino)methyl)-5-bromopyridine; 5-Bromo-3-((Boc-amino)methyl)pyridine; Boc-5-Bromo-3-aminomethylpyridine; 5-Bromo-3-(Boc-aminomethyl)pyridine; (5-Bromopyridin-3-yl)methylcarbamic acid tert-butyl ester; N-Boc-3-(aminomethyl)-5-bromopyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Bromopyridin-3-Ylmethylcarbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single impurity	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.