Description

5-Bromo-1-Methyl-1H-Pyrazin-2-One is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Acts as a building block for creating specialized polymers, ligands, or organic electronic materials due to its functionalized pyrazinone ring.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Academic & Contract Research: Essential for methodological development and exploratory chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	5-Bromo-1-Methyl-1H-Pyrazin-2-One
CAS No.	1243288-53-0
Molecular Formula	C5H5BrN2O
Molecular Weight	189.01 g/mol
Synonyms	5-Bromo-1-methylpyrazin-2(1H)-one; 1-Methyl-5-bromo-1H-pyrazin-2-one; 5-Bromo-1-methyl-1,2-dihydropyrazin-2-one; 5-Bromo-1-methyl-2(1H)-pyrazinone; 2(1H)-Pyrazinone, 5-bromo-1-methyl-; 1243288-53-0; 5-Bromo-1-methyl-1H-pyrazin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-Methyl-1H-Pyrazin-2-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance in cGMP (current Good Manufacturing Practice) environments for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.