Description

n-Methyl-6-(Trifluoromethyl)Pyridin-2-Amine CAS NO 1242339-20-3 is a high-value trifluoromethylated pyridine derivative, a key building block prized for its ability to impart metabolic stability and lipophilicity to target molecules. Its primary commercial value lies in serving as a sophisticated intermediate in the research and development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to optimize lead compounds.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of drug candidates targeting various therapeutic areas, leveraging the trifluoromethyl group's bioisosteric properties.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the pyridine core and fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized ligands in catalysis or for creating specialty polymers with unique electronic properties.
• Chemical Biology Probes: Employed in the design of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards for advanced clients.

Basic Information

Product Name	n-Methyl-6-(Trifluoromethyl)Pyridin-2-Amine
CAS No.	1242339-20-3
Molecular Formula	C7H7F3N2
Molecular Weight	176.14 g/mol
Synonyms	2-Amino-6-(trifluoromethyl)-N-methylpyridine; 6-(Trifluoromethyl)-2-(methylamino)pyridine; N-Methyl-2-amino-6-(trifluoromethyl)pyridine; 2-(Methylamino)-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-N-methylpyridin-2-amine; 1242339-20-3; N-Methyl-6-trifluoromethylpyridin-2-amine
EINECS	Contact for details

Quality Control

Every batch of n-Methyl-6-(Trifluoromethyl)Pyridin-2-Amine is produced and tested under a strict quality management system to ensure consistency and reliability for your critical R&D and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with the standards expected for advanced pharmaceutical intermediates, supporting development under ISO and cGMP frameworks where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.