Description

1H-Pyrazolo[4,3-C]Pyridine-3-Carboxylic Acid, 4,5,6,7-Tetr is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrazolopyridine chemical class. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing innovative therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Integral to the synthetic route of investigational new drugs (INDs) requiring the pyrazolopyridine pharmacophore.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for analytical method development in pharmacokinetic studies.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis and scale-up projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for heterocyclic chemistry studies and the development of new synthetic methodologies.

Basic Information

Item	Detail
Product Name	1H-Pyrazolo[4,3-C]Pyridine-3-Carboxylic Acid, 4,5,6,7-Tetr
CAS No.	1242339-11-2
Molecular Formula	C7H3N3O2
Molecular Weight	161.12 g/mol
Synonyms	4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid; Tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid; 1H-Pyrazolo[4,3-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-; 1242339-11-2; Pyrazolopyridine-3-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Every batch of 1H-Pyrazolo[4,3-C]Pyridine-3-Carboxylic Acid, 4,5,6,7-Tetr is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment. Our quality commitment aligns with ICH guidelines for impurities in drug substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is sensitive to strong acids and organic solvents; ensure proper segregation in storage. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.