Description

5-Chloro-3-Methoxypyridin-2-Amine is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, enabling precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific chloro and methoxy substituents onto a pyridine scaffold.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides that require a halogenated methoxypyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive compounds.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in fine chemical production.
• Bioconjugation and Probe Development: The amine functionality allows for conjugation, making it useful in creating biochemical probes and diagnostic agents.

Basic Information

Product Name	5-Chloro-3-Methoxypyridin-2-Amine
CAS No.	1242336-53-3
Molecular Formula	C6H7ClN2O
Molecular Weight	158.58 g/mol
Synonyms	2-Amino-5-chloro-3-methoxypyridine; 5-Chloro-3-methoxy-2-pyridinamine; 3-Methoxy-5-chloropyridin-2-amine; 2-Pyridinamine, 5-chloro-3-methoxy-; 5-Chloro-3-methoxypyridin-2-ylamine; 5-Chloro-3-methoxy-2-aminopyridine
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Methoxypyridin-2-Amine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure compliance with exacting standards for fine chemical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.