Description

2-Iodo-6-Morpholinopyrazine is a high-value, functionalized heterocyclic building block designed for advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical research and agrochemical discovery. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a halogenated, nitrogen-rich pyrazine core into their target structures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and other small-molecule drug discovery programs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialized polymers, ligands, or organic electronic materials.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create more complex biaryl or alkynyl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Ligand Synthesis for Catalysis: Acts as a starting material for creating novel nitrogen-donor ligands used in homogeneous catalysis.

Basic Information

Product Name	2-Iodo-6-Morpholinopyrazine
CAS No.	1242241-01-5
Molecular Formula	C8H10IN3O
Molecular Weight	291.09 g/mol
Synonyms	6-Morpholino-2-iodopyrazine; 2-Iodo-6-morpholin-4-ylpyrazine; Pyrazine, 2-iodo-6-morpholino-; 2-Iodo-6-(4-morpholinyl)pyrazine; 1242241-01-5; 2-Iodo-6-morpholin-4-yl-pyrazine
EINECS	Contact for details

Quality Control

Our 2-Iodo-6-Morpholinopyrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.