Description

(S)-1-Boc-2-Isopropyl-Piperazine Hcl is a high-purity chiral piperazine derivative, serving as a critical building block in modern pharmaceutical synthesis. This compound matters for its role in constructing complex molecules with defined stereochemistry, enabling the development of targeted therapeutics. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and other specialized medicinal chemistry applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially those targeting neurological and psychiatric disorders.
• API Development: Used in research and process development for constructing the core scaffold of potential Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective chemical reactions to introduce the (S)-configured isopropyl-piperazine moiety.
• Medicinal Chemistry Research: A valuable building block for creating focused libraries of compounds for structure-activity relationship (SAR) studies in drug discovery programs.
• Peptidomimetics: Incorporated into the design and synthesis of peptide mimics to enhance metabolic stability and bioavailability.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for use in cGMP-compliant production of clinical trial materials and commercial drugs.

Basic Information

Product Name	(S)-1-Boc-2-Isopropyl-Piperazine Hcl
CAS No.	1241725-73-4
Molecular Formula	C12H25ClN2O2
Molecular Weight	264.79 g/mol
Synonyms	(S)-1-(tert-Butoxycarbonyl)-2-(propan-2-yl)piperazine hydrochloride; (S)-2-Isopropyl-1-Boc-piperazine hydrochloride; (S)-1-Boc-2-(1-Methylethyl)piperazine HCl; tert-Butyl (S)-2-isopropylpiperazine-1-carboxylate hydrochloride; (S)-1-N-Boc-2-isopropylpiperazine hydrochloride; (S)-2-Isopropylpiperazine-1-carboxylic acid tert-butyl ester hydrochloride; Boc-(S)-2-iPr-piperazine·HCl
EINECS	Contact for details

Quality Control

Our (S)-1-Boc-2-Isopropyl-Piperazine Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.