Description

(S)-2-(3,4-Difluorophenyl)Piperidine is a high-purity chiral piperidine derivative, a crucial building block in modern pharmaceutical research and development. Its value lies in its role as a key intermediate for synthesizing active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders and other therapeutic areas. This compound is essential for medicinal chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries seeking to develop novel, enantiomerically pure drug candidates.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug discovery programs.
• CNS Drug Development: Serves as a key structural motif in the synthesis of potential therapeutics for neurological and psychiatric conditions.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand in catalytic asymmetric reactions to induce stereoselectivity.
• Process Chemistry: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(S)-2-(3,4-Difluorophenyl)Piperidine
CAS No.	1241683-84-0
Molecular Formula	C11H13F2N
Molecular Weight	197.23 g/mol
Synonyms	(S)-2-(3,4-Difluorophenyl)piperidine; (S)-3,4-Difluoro-2-piperidin-2-ylbenzene; (S)-2-(3,4-Difluorophenyl)piperidine; (S)-2-(3,4-Difluorophenyl)piperidine hydrochloride; (S)-2-(3,4-Difluorophenyl)piperidine HBr; 2-(3,4-Difluorophenyl)piperidine, (S)-; (S)-2-(3,4-Difluorophenyl)piperidine free base
EINECS	Contact for details

Quality Control

Our (S)-2-(3,4-Difluorophenyl)Piperidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.