Description

6-Methoxy-5-(4-Methyl-1H-Imidazol-1-Yl)Picolinonitrile is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic structure. This compound is of significant commercial interest as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for oncology, anti-inflammatory, and central nervous system (CNS) agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Drug Discovery Research: Serves as a versatile scaffold for medicinal chemistry, enabling the exploration of structure-activity relationships (SAR) in new chemical entities.
• Process Chemistry & Scale-Up: Used in the development and optimization of robust, scalable synthetic routes for potential commercial API manufacturing.
• Biochemical Research: May be employed as a tool compound or ligand in biochemical assays to study specific enzyme or receptor interactions.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial compounds for client-specific research programs.

Basic Information

Product Name	6-Methoxy-5-(4-Methyl-1H-Imidazol-1-Yl)Picolinonitrile
CAS No.	1241428-31-8
Molecular Formula	C11H10N4O
Molecular Weight	214.23 g/mol
Synonyms	6-Methoxy-5-(4-methylimidazol-1-yl)picolinonitrile; 5-(4-Methyl-1H-imidazol-1-yl)-6-methoxypicolinonitrile; 2-Cyano-6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridine; 1241428-31-8; 6-Methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridine-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 6-Methoxy-5-(4-Methyl-1H-Imidazol-1-Yl)Picolinonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.