Description

Octreotide Acetate Salt is a synthetic cyclic octapeptide analog of somatostatin, formulated as its acetate salt to enhance stability and solubility. This high-purity active pharmaceutical ingredient (API) is critical for its potent inhibitory effects on the secretion of growth hormone, glucagon, and insulin. It is essential for pharmaceutical manufacturers developing targeted therapeutic solutions, primarily in the treatment of acromegaly, neuroendocrine tumors (NETs), and severe diarrhea associated with certain cancers.

Application

• Pharmaceutical API: Primary active ingredient in injectable formulations for the treatment of acromegaly and gigantism.
• Oncology Therapeutics: Key component in medications for symptom control and tumor growth inhibition in neuroendocrine tumors (NETs).
• Gastroenterology: Used in therapies for severe diarrhea and flushing associated with metastatic carcinoid tumors and vasoactive intestinal peptide-secreting tumors (VIPomas).
• Endocrine Disorder Management: Employed in conditions related to excessive hormone secretion from the pituitary or pancreas.
• Research & Development: Vital reference standard and building block in peptide research, drug discovery, and biochemical studies.
• Long-Acting Release (LAR) Formulations: Serves as the core API in depot formulations designed for sustained, controlled release over weeks.

Basic Information

Product Name	Octreotide Acetate Salt
CAS No.	1240797-41-4
Molecular Formula	C49H66N10O10S2 • xC2H4O2
Molecular Weight	1019.24 g/mol (free base)
Synonyms	Octreotide Acetate; SMS 201-995 Acetate; Sandostatin® Acetate; D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2→7)-disulfide acetate; BIM-23014 Acetate; Somatostatin Octapeptide Analog Acetate
EINECS	Contact for details

Quality Control

Our Octreotide Acetate Salt is manufactured under strict quality systems and undergoes rigorous analytical testing to ensure it meets the highest standards for pharmaceutical use. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant ICH guidelines and can supply material that aligns with pharmacopeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and potency. For long-term storage, consider desiccated conditions at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Acetic Acid Content	5.0% - 12.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.