Description

2-Bromo-6-(4-Methoxybenzyloxy)Pyridine is a high-value brominated pyridine derivative with a methoxybenzyl protecting group, serving as a critical synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing active pharmaceutical ingredients (APIs) and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the pyridine core's bioactivity.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and coordination chemistry.
• Material Science: Intermediate in the production of organic electronic materials and liquid crystals.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Chemical Biology Probes: Used to create tagged or modified molecules for studying biological pathways and target engagement.

Basic Information

Product Name	2-Bromo-6-(4-Methoxybenzyloxy)Pyridine
CAS No.	1240620-34-1
Molecular Formula	C14H14BrNO2
Molecular Weight	308.17 g/mol
Synonyms	2-Bromo-6-[(4-methoxyphenyl)methoxy]pyridine; 6-[(4-Methoxybenzyl)oxy]-2-bromopyridine; 2-Bromo-6-(p-methoxybenzyloxy)pyridine; 2-Bromo-6-(4-methoxybenzyloxy)pyridine; PMB-protected 2-bromo-6-hydroxypyridine; 2-Br-6-PMB-O-Pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-(4-Methoxybenzyloxy)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) that include data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP standards for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.