Description

2-(5-Bromopyridin-3-Yl)-2-Methylpropan-1-Ol is a high-purity brominated pyridine derivative, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in providing a functionalized pyridine core with a sterically hindered alcohol side chain, enabling precise molecular construction for complex target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the bromopyridine moiety contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers due to its aromatic and modifiable structure.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	2-(5-Bromopyridin-3-Yl)-2-Methylpropan-1-Ol
CAS No.	1240605-07-5
Molecular Formula	C9H12BrNO
Molecular Weight	230.10 g/mol
Synonyms	2-(5-Bromo-3-pyridinyl)-2-methyl-1-propanol; 2-Methyl-2-(5-bromopyridin-3-yl)propan-1-ol; 5-Bromo-3-(2-hydroxy-2-methylpropyl)pyridine; 3-(2-Hydroxy-2-methylpropyl)-5-bromopyridine; 1240605-07-5; 2-(5-Bromopyridin-3-yl)-2-methylpropan-1-ol
EINECS	Contact for details

Quality Control

Our 2-(5-Bromopyridin-3-Yl)-2-Methylpropan-1-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up applications. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC/GC purity data, identity confirmation (IR, NMR), and impurity profiles. Our quality commitment aligns with ISO standards, and we support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.