Description

7-Bromo-3-Chloro-Pyrido[2,3-B]Pyrazine is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because it provides a versatile and reactive scaffold for constructing complex molecular architectures, particularly in pharmaceutical discovery. Researchers and process chemists in the pharmaceutical, agrochemical, and material science industries need it to develop new active ingredients and functional molecules. Its specific halogen substitution pattern offers precise sites for further functionalization via cross-coupling and nucleophilic substitution reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Cross-Coupling Reactions: The bromo and chloro substituents make it an excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions.
• Library Synthesis: A valuable scaffold for generating diverse compound libraries in high-throughput screening and medicinal chemistry programs.

Basic Information

Product Name	7-Bromo-3-Chloro-Pyrido[2,3-B]Pyrazine
CAS No.	1240594-95-9
Molecular Formula	C7H3BrClN3
Molecular Weight	244.48 g/mol
Synonyms	7-Bromo-3-chloropyrido[2,3-b]pyrazine; 3-Chloro-7-bromopyrido[2,3-b]pyrazine; Pyrido[2,3-b]pyrazine, 7-bromo-3-chloro-; 1240594-95-9; 7-Bromo-3-chloro-[1,2,4]triazolo[4,3-a]pyrazine (incorrect but common misnomer search term); 7-Br-3-Cl-Pyrido[2,3-b]pyrazine; BCPP (abbreviation)
EINECS	Contact for details

Quality Control

Our 7-Bromo-3-Chloro-Pyrido[2,3-B]Pyrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with the standards required for research and development under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.