Description

(R)-6-Oxopiperazine-2-Carboxylic Acid CAS NO 1240590-33-3 is a high-purity, non-proteinogenic amino acid derivative belonging to the piperazine class, serving as a critical chiral building block in advanced organic synthesis. Its value lies in its rigid, bicyclic structure and defined stereochemistry, which are essential for constructing complex molecules with precise three-dimensional architecture. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in drug discovery, particularly in the development of protease inhibitors and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for protease inhibitors and other enzyme-targeted therapies.
• Peptidomimetics Research: Used to construct constrained peptide analogs and peptidomimetics to enhance metabolic stability and bioavailability in drug candidates.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Incorporated into molecular probes for studying enzyme mechanisms and protein-protein interactions.
• Academic & Industrial R&D: Employed in research laboratories for methodological development in organic and medicinal chemistry.

Basic Information

Item	Details
Product Name	(R)-6-Oxopiperazine-2-Carboxylic Acid
CAS No.	1240590-33-3
Molecular Formula	C5H8N2O3
Molecular Weight	144.13 g/mol
Synonyms	(R)-2-Carboxy-6-oxopiperazine; (R)-6-Oxo-2-piperazinecarboxylic Acid; (R)-Piperazine-2-carboxylic acid, 6-oxo-; (2R)-6-Oxopiperazine-2-carboxylic acid; (R)-2-Piperazinecarboxylic acid, 6-oxo-; (R)-1,4-Diazinane-2-carboxylic acid, 6-oxo-; (R)-6-Ketopiperazine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our (R)-6-Oxopiperazine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity standards suitable for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.