Description

(R)-5-Oxopiperazine-2-Carboxylic Acid CAS NO 1240590-31-1 is a high-purity, non-proteinogenic amino acid derivative featuring a chiral center, making it a critical building block in advanced organic synthesis. Its value lies in its role as a key chiral intermediate for constructing complex pharmacologically active molecules, particularly in the development of novel therapeutics. This compound is essential for research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require enantiomerically pure intermediates for drug discovery and API manufacturing.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for protease inhibitors and other targeted therapies.
• Peptidomimetic Chemistry: Used in the design and synthesis of peptidomimetics and constrained peptides to improve metabolic stability and bioavailability of drug candidates.
• Asymmetric Synthesis: Serves as a chiral scaffold or starting material for the asymmetric synthesis of more complex, biologically active molecules.
• Chemical Biology Research: Employed as a tool compound or building block in chemical biology for studying enzyme mechanisms and protein-ligand interactions.
• Ligand Development: Utilized in the creation of novel chelating agents or ligands for catalysis and metal coordination chemistry.
• Fine Chemical Production: Acts as a specialized intermediate in the custom synthesis of high-value fine chemicals for various industrial applications.

Basic Information

Product Name	(R)-5-Oxopiperazine-2-Carboxylic Acid
CAS No.	1240590-31-1
Molecular Formula	C5H8N2O3
Molecular Weight	144.13 g/mol
Synonyms	(R)-2-Carboxy-5-oxopiperazine; (R)-5-Oxo-2-piperazinecarboxylic Acid; (2R)-5-Oxopiperazine-2-carboxylic acid; D-5-Oxopiperazine-2-carboxylic Acid; (R)-2-Piperazinecarboxylic acid, 5-oxo-; (R)-Aminopiperazine-2-carboxylic acid derivative; (R)-Hydantoin-5-acetic acid derivative; (R)-Ureidopropionic acid derivative
EINECS	Contact for details

Quality Control

Our (R)-5-Oxopiperazine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.