Description

(R)-2-Cyclopropyl-Piperazine CAS NO 1240589-80-3 is a high-purity, single-enantiomer chiral piperazine derivative, serving as a critical building block in modern organic synthesis. Its value lies in providing a stereochemically defined, functionalized scaffold essential for constructing complex molecules with targeted biological activity. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, process development, and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets and anti-infectives.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization to introduce the cyclopropyl-piperazine moiety into drug candidates.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Research: Serves as a building block for developing new crop protection agents and pesticides with enhanced efficacy.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Process Chemistry: Integrated into scalable synthetic routes for the commercial production of enantiomerically pure pharmaceuticals.

Basic Information

Item	Detail
Product Name	(R)-2-Cyclopropyl-Piperazine
CAS No.	1240589-80-3
Molecular Formula	C7H14N2
Molecular Weight	126.20 g/mol
Synonyms	(R)-2-Cyclopropylpiperazine; (R)-2-Cyclopropyl-1,4-diazacyclohexane; (R)-2-Cyclopropyldiazinane; (R)-2-Cycloprylpiperazine; (R)-2-Cyclopropyl-piperazine; (2R)-2-Cyclopropylpiperazine; (R)-(-)-2-Cyclopropylpiperazine; UNII-1V8N8U4F1M
EINECS	Contact for details

Quality Control

Our (R)-2-Cyclopropyl-Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.