Description

(5R)-5-Methyl-2-piperazinone is a high-purity chiral piperazinone derivative, a crucial building block in modern pharmaceutical synthesis. Its value lies in its role as a key intermediate for creating complex, biologically active molecules with defined stereochemistry. This compound is essential for research and development chemists and production teams in the pharmaceutical and agrochemical industries, particularly those focused on developing novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used as a building block in the development of advanced pesticides and herbicides with specific stereochemical requirements.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric hydrogenation and other catalytic processes.
• Peptidomimetics Research: Employed in medicinal chemistry for the design and construction of peptidomimetic compounds that mimic natural peptides.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key requested intermediate for custom synthesis projects requiring high stereochemical purity.

Basic Information

Product Name	(5R)-5-Methyl-2-piperazinone
CAS No.	1240589-51-8
Molecular Formula	C5H10N2O
Molecular Weight	114.15 g/mol
Synonyms	(R)-5-Methyl-2-piperazinone; (R)-5-Methylpiperazin-2-one; 5-Methyl-2-piperazinone, (5R)-; 2-Piperazinone, 5-methyl-, (5R)-; (R)-5-Methyl-3,4,5,6-tetrahydropyrazin-2(1H)-one
EINECS	Contact for details

Quality Control

Our (5R)-5-Methyl-2-piperazinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming specifications for identity, purity, and chiral purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.