Description

(S)-4-(tert-Butoxycarbonyl)-6-Oxopiperazine-2-Carboxylic Acid is a high-purity, non-natural amino acid derivative and a key chiral building block in advanced organic synthesis. This compound is critical for the development of complex pharmaceutical molecules, particularly in the synthesis of peptide-based drugs and protease inhibitors. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in oncology and antiviral research.
• Peptidomimetic Chemistry: Serves as a constrained scaffold for designing and constructing novel peptide mimics with enhanced metabolic stability.
• Protease Inhibitor Development: Used in the research and production of inhibitors targeting specific enzymes like HCV NS3/4A protease.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Asymmetric Synthesis: Acts as a starting material or intermediate in catalytic asymmetric reactions to introduce chiral complexity.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the cGMP production of clinical trial materials and commercial APIs.

Basic Information

Product Name	(S)-4-(tert-Butoxycarbonyl)-6-Oxopiperazine-2-Carboxylic Acid
CAS No.	1240586-09-7
Molecular Formula	C11H18N2O5
Molecular Weight	258.27 g/mol
Synonyms	(2S)-4-[(2-Methylpropan-2-yl)oxycarbonyl]-6-oxopiperazine-2-carboxylic acid; (S)-Boc-6-oxopiperazine-2-carboxylic acid; (S)-1-Boc-3,5-dioxopiperazine-2-carboxylic acid; (S)-1-(tert-Butoxycarbonyl)-3,5-dioxopiperazine-2-carboxylic acid; (S)-4-(Boc)-2,6-diketopiperazine-2-carboxylic acid; (S)-N-Boc-2,6-dioxopiperazine-3-carboxylic acid; 1240586-09-7; (S)-Boc-DKP-COOH
EINECS	Contact for details

Quality Control

Our (S)-4-(tert-Butoxycarbonyl)-6-Oxopiperazine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to maintain stability and purity. Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.