Description

(2S,5S)-2,5-Diisobutyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, stereochemically defined piperazine derivative used as a critical chiral building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular architecture, particularly in the development of active pharmaceutical ingredients (APIs) and complex bioactive molecules. It is primarily targeted at the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including protease inhibitors and other small molecule drugs.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for synthesizing sophisticated ligands used in enantioselective catalysis.
• Agrochemical Synthesis: Employed in the creation of chiral active ingredients for advanced crop protection products.
• Peptidomimetics Research: Used to construct constrained peptide analogs and other biologically active scaffolds in drug discovery.
• Custom Chemical Synthesis: A valuable building block for contract research organizations (CROs) and CDMOs producing complex, bespoke molecules for clients.

Basic Information

Product Name	(2S,5S)-2,5-Diisobutyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1240585-98-1
Molecular Formula	C16H32N2O2
Molecular Weight	284.44 g/mol
Synonyms	tert-Butyl (2S,5S)-2,5-diisobutylpiperazine-1-carboxylate; (2S,5S)-1-Boc-2,5-diisobutylpiperazine; (2S,5S)-2,5-Diisobutyl-1-Boc-piperazine; 1-Boc-2,5-diisobutylpiperazine (2S,5S); 1-(tert-Butoxycarbonyl)-2,5-diisobutylpiperazine (2S,5S); (2S,5S)-1-(tert-Butoxycarbonyl)-2,5-diisobutylpiperazine; Boc-(2S,5S)-2,5-diisobutylpiperazine
EINECS	Contact for details

Quality Control

Our (2S,5S)-2,5-Diisobutyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.