Description

(R)-3-Phenyl-Piperazin-2-One CAS NO 1240585-54-9 is a high-purity chiral piperazinone derivative, serving as a critical building block in advanced pharmaceutical synthesis. Its enantiopure nature is essential for developing active pharmaceutical ingredients (APIs) with specific stereochemical requirements, ensuring optimal efficacy and safety profiles. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents, particularly within the central nervous system (CNS) and oncology fields.

Application

• Key chiral intermediate in the synthesis of novel pharmaceutical candidates.
• Building block for research into serotonin and dopamine receptor modulators.
• Precursor in the development of potential antipsychotic and antidepressant agents.
• Intermediate for creating libraries of bioactive compounds in medicinal chemistry.
• Starting material for the synthesis of complex heterocyclic molecules in process R&D.
• Reference standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	(R)-3-Phenyl-Piperazin-2-One
CAS No.	1240585-54-9
Molecular Formula	C10H12N2O
Molecular Weight	176.22 g/mol
Synonyms	(R)-3-Phenylpiperazin-2-one; (R)-3-Phenyl-2-piperazinone; (3R)-3-Phenylpiperazin-2-one; (R)-3-Phenyl-1,4-diazinan-2-one; (R)-3-Phenyl-2-oxopiperazine; (R)-3-Phenyl-2-piperazone; (R)-3-Phenyl-2-ketopiperazine; (R)-3-Phenyl-2-piperazin-1-one
EINECS	Contact for details

Quality Control

Our (R)-3-Phenyl-Piperazin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and process development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.