Description

(S)-3-Phenyl-Piperazin-2-One is a chiral piperazinone derivative, a high-value pharmaceutical intermediate and building block. Its enantiopure nature is critical for developing active pharmaceutical ingredients (APIs) with specific stereochemical requirements, ensuring efficacy and safety. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutics, particularly in central nervous system (CNS) and oncology drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs), especially those targeting neurological pathways.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective chemical transformations.
• Biochemical Research: Potential use as a reference standard or probe in biochemical assays and pharmacological studies.

Basic Information

Product Name	(S)-3-Phenyl-Piperazin-2-One
CAS No.	1240585-52-7
Molecular Formula	C10H12N2O
Molecular Weight	176.22 g/mol
Synonyms	(S)-3-Phenylpiperazin-2-one; (S)-3-Phenyl-2-piperazinone; (S)-1,4-Diaza-2-oxo-3-phenylcyclohexane; (3S)-3-Phenylpiperazin-2-one; (S)-3-Phenyl-1,4-diazinan-2-one; (S)-3-Phenyl-2-ketopiperazine; (S)-2-Oxo-3-phenylpiperazine
EINECS	Contact for details

Quality Control

Our (S)-3-Phenyl-Piperazin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.