Description

S-1-Boc-2-Phenylpiperazine is a protected piperazine derivative of significant importance in pharmaceutical research and development. This compound serves as a crucial advanced pharmaceutical intermediate (API intermediate) for constructing complex molecules, particularly in medicinal chemistry. It is primarily utilized by research institutions, CROs/CDMOs, and pharmaceutical companies engaged in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing a piperazine pharmacophore.
• Medicinal Chemistry Research: Used in the discovery and optimization of new chemical entities for drug development programs.
• CNS Drug Synthesis: Integral in creating potential therapeutics for neurological and psychiatric conditions, such as antidepressants, antipsychotics, and anxiolytics.
• Peptidomimetics & Scaffold Development: Employed in the design of peptide mimics and novel molecular scaffolds for probing biological pathways.
• Contract Manufacturing: Supplied to CDMOs for the scale-up and cGMP production of clinical trial materials and commercial APIs.
• Chemical Library Synthesis: Used to generate diverse compound libraries for high-throughput screening (HTS) in early-stage drug discovery.

Basic Information

Product Name	S-1-Boc-2-Phenylpiperazine
CAS No.	1240583-48-5
Molecular Formula	C15H22N2O2
Molecular Weight	262.35 g/mol
Synonyms	1-Boc-2-Phenylpiperazine; tert-Butyl 2-phenylpiperazine-1-carboxylate; 2-Phenyl-1-(tert-butoxycarbonyl)piperazine; 1-(tert-Butoxycarbonyl)-2-phenylpiperazine; (S)-1-Boc-2-phenylpiperazine; (S)-tert-Butyl 2-phenylpiperazine-1-carboxylate; S-1-Boc-2-phenylpiperazine; 1240583-48-5
EINECS	Contact for details

Quality Control

Our S-1-Boc-2-Phenylpiperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment. We support development from research to commercial scale with consistent quality, meeting the stringent requirements of pharmaceutical R&D and cGMP production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use. Recommended long-term storage temperature is 2-8°C (refrigerated). Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.