Description

(S)-3-(4-Methoxy-Benzyl)-Piperazin-2-One is a high-purity chiral piperazinone derivative, a crucial building block in modern pharmaceutical research and development. Its defined stereochemistry and functionalized structure make it an essential intermediate for synthesizing targeted bioactive molecules. This compound is primarily required by pharmaceutical and biotechnology companies for the development of new therapeutic agents, particularly in areas such as central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Drug Discovery: Used as a core scaffold or building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• CNS Drug Development: Particularly relevant for creating potential therapeutics targeting neurological and psychiatric conditions.
• Preclinical Research: Serves as a critical material in the synthesis of candidate compounds for pharmacological evaluation.
• Process Chemistry: Employed in the development and optimization of scalable synthetic routes for advanced intermediates.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services.

Basic Information

Product Name	(S)-3-(4-Methoxy-Benzyl)-Piperazin-2-One
CAS No.	1240583-47-4
Molecular Formula	C13H18N2O2
Molecular Weight	234.30 g/mol
Synonyms	(S)-3-(4-Methoxybenzyl)piperazin-2-one; (3S)-3-[(4-Methoxyphenyl)methyl]piperazin-2-one; (S)-3-(p-Methoxybenzyl)-2-piperazinone; (S)-3-(4-Methoxybenzyl)-2-piperazinone; (S)-3-(4-Methoxybenzyl)piperazin-2-one; (S)-3-(4-Methoxybenzyl)-2-piperazinone; 1240583-47-4; (S)-3-(4-Methoxybenzyl)piperazin-2-one
EINECS	Contact for details

Quality Control

Our (S)-3-(4-Methoxy-Benzyl)-Piperazin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.