Description

(5S)-5-Methyl-2-Piperazinone CAS NO 1240583-20-3 is a high-purity, chiral piperazinone derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules with precise biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific chirality impacts efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetic Research: Incorporated into peptide analogs to modulate stability, bioavailability, and receptor binding properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring high stereochemical purity and reliable supply.

Basic Information

Product Name	(5S)-5-Methyl-2-Piperazinone
CAS No.	1240583-20-3
Molecular Formula	C5H10N2O
Molecular Weight	114.15 g/mol
Synonyms	(5S)-5-Methylpiperazin-2-one; (S)-5-Methyl-2-piperazinone; 5-Methyl-2-piperazinone, (5S)-; 2-Piperazinone, 5-methyl-, (5S)-; (S)-5-Methylpiperazin-2-one; (5S)-5-Methyl-3,4,5,6-tetrahydro-2H-pyrazin-2-one; L-5-Methyl-2-piperazinone
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chiral intermediates. Production follows current Good Manufacturing Practices (cGMP) where applicable, and each batch is analyzed to ensure compliance with exacting purity and enantiomeric excess standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.