Description

(S)-3-Cyclopropyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, chiral piperazine derivative serving as a critical building block in modern organic synthesis. This compound matters for its role as a key intermediate in the development of novel, biologically active molecules, particularly in the pharmaceutical sector. It is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents, including central nervous system (CNS) drugs and other small-molecule pharmaceuticals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for CNS-targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to introduce the cyclopropyl-piperazine moiety into candidate molecules.
• Process Chemistry: Serves as a standardized, high-purity starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or scaffold in the synthesis of enantiomerically pure compounds for biological testing.
• Contract Research & Manufacturing (CRAM): Supplied to organizations offering custom synthesis and process development services for the global pharmaceutical industry.

Basic Information

Product Name	(S)-3-Cyclopropyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1240582-07-3
Molecular Formula	C12H22N2O2
Molecular Weight	226.32 g/mol
Synonyms	tert-Butyl (S)-3-cyclopropylpiperazine-1-carboxylate; (S)-1-Boc-3-cyclopropylpiperazine; (S)-3-Cyclopropyl-1-(tert-butoxycarbonyl)piperazine; (S)-N-Boc-3-cyclopropylpiperazine; (S)-1-N-Boc-3-cyclopropylpiperazine; (S)-3-Cyclopropylpiperazine-1-carboxylic acid tert-butyl ester; (S)-3-Cyclopropyl-1-Boc-piperazine; (S)-Boc-3-cyclopropylpiperazine
EINECS	Contact for details

Quality Control

Our (S)-3-Cyclopropyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure high chemical and chiral purity suitable for research and pharmaceutical applications. Each batch is characterized by advanced analytical techniques including HPLC, GC, and NMR to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.