Description

1-(Piperazin-1-Yl)-2-(Pyridin-2-Yl)Ethan-1-One Dihydrochloride is a high-purity, specialized organic salt with significant utility in advanced chemical synthesis. This compound serves as a critical building block and intermediate for the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and the synthesis of compound libraries for high-throughput screening.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a building block in the multi-step synthesis of complex APIs, where its piperazine and pyridine motifs are integral to biological activity.
• Agrochemical Development: Employed in the synthesis of novel pesticides and herbicides, leveraging its heterocyclic structure.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and biological pathways.
• Fine Chemical Synthesis: Acts as an intermediate for producing specialty chemicals used in advanced material science and catalysis.

Basic Information

Product Name	1-(Piperazin-1-Yl)-2-(Pyridin-2-Yl)Ethan-1-One Dihydrochloride
CAS No.	1240527-21-2
Molecular Formula	C11H16N3O·2HCl
Molecular Weight	279.19 g/mol (Free base: 206.27 g/mol)
Synonyms	2-(2-Pyridinyl)-1-(1-piperazinyl)ethanone dihydrochloride; 1-Piperazineacetophenone, 2-pyridyl-, dihydrochloride; N-(2-Pyridin-2-ylethyl)piperazine-1-carboxamide dihydrochloride (related structure); Pyridin-2-yl(piperazin-1-yl)methanone dihydrochloride derivative; CAS 1240527-21-2
EINECS	Contact for details

Quality Control

Our 1-(Piperazin-1-Yl)-2-(Pyridin-2-Yl)Ethan-1-One Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.