Description

(S)-1,3-Dimethyl-Piperazin-2-One is a high-purity, chiral piperazinone derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate stereochemically defined, nitrogen-containing heterocycles into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Research: Used in the synthesis of advanced, biologically active molecules for crop protection and pest management.
• Fine Chemical Synthesis: Serves as a versatile intermediate for creating complex, high-value specialty chemicals and functional materials.
• Academic & Process Chemistry: A valuable reagent for methodological development in organic chemistry and for scaling up synthetic routes in process R&D.

Basic Information

Product Name	(S)-1,3-Dimethyl-Piperazin-2-One
CAS No.	1240300-34-8
Molecular Formula	C7H14N2O
Molecular Weight	142.20 g/mol
Synonyms	(S)-1,3-Dimethylpiperazin-2-one; (S)-1,3-Dimethyl-2-piperazinone; (3S)-1,3-Dimethyl-3,4-dihydro-2H-pyrazin-2-one; (S)-1,3-Dimethyl-3,4-dihydro-2H-pyrazin-2-one; (S)-1,3-Dimethyl-3,4-dihydro-2(1H)-pyrazinone; (S)-1,3-Dimethyl-1,2,3,4-tetrahydropyrazin-2-one
EINECS	Contact for details

Quality Control

Our (S)-1,3-Dimethyl-Piperazin-2-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.