Description

(R)-1,3-Dimethyl-Piperazin-2-One is a high-purity chiral piperazinone derivative, a crucial building block in modern organic synthesis. Its value lies in its role as a key intermediate for constructing complex, biologically active molecules with defined stereochemistry. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Asymmetric Synthesis: Used as a building block or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers.
• Ligand and Catalyst Development: Serves as a precursor for novel chiral ligands and organocatalysts used in enantioselective transformations.
• Medicinal Chemistry Research: Employed in the design and synthesis of novel compound libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry: Utilized in the development and scale-up of efficient synthetic routes for target molecules under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	(R)-1,3-Dimethyl-Piperazin-2-One
CAS No.	1240300-33-7
Molecular Formula	C7H14N2O
Molecular Weight	142.20 g/mol
Synonyms	(R)-1,3-Dimethylpiperazin-2-one; (R)-1,3-Dimethyl-2-piperazinone; (R)-1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrazinone; (R)-1,3-Dimethyl-1,4-diazepan-2-one; (R)-1,3-Dimethylpiperazinone; (R)-DMPO; (R)-enantiomer of 1,3-Dimethylpiperazin-2-one
EINECS	Contact for details

Quality Control

Our (R)-1,3-Dimethyl-Piperazin-2-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive analytical data, including chiral purity (enantiomeric excess) verification by HPLC. A detailed Certificate of Analysis (COA) is supplied with each batch, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.