Description

m-Peg13-Acid CAS NO 1239588-11-4 is a monodisperse polyethylene glycol (PEG) derivative featuring a carboxylic acid functional group at one terminus and a methoxy group at the other. This bifunctional linker is critical for creating stable, hydrophilic conjugates in advanced pharmaceutical and biotech applications. It is primarily used by researchers and manufacturers in drug delivery, bioconjugation, and materials science who require precise, high-purity PEG spacers to enhance solubility, reduce immunogenicity, and prolong circulation time of therapeutic agents.

Application

• Bioconjugation and Drug Delivery: A key linker for attaching therapeutic payloads (e.g., antibodies, peptides, small molecules) to create antibody-drug conjugates (ADCs) and other targeted delivery systems.
• PEGylation Reagent: Used to PEGylate proteins, peptides, and nanoparticles to improve their pharmacokinetic profile, stability, and solubility.
• Polymer and Biomaterial Synthesis: Serves as a functional monomer or cross-linker for synthesizing hydrogels, smart polymers, and biocompatible coatings.
• Diagnostic Reagents: Employed in the development of diagnostic assays and imaging probes where a hydrophilic spacer is needed to attach labels or detection moieties.
• Surface Functionalization: Used to modify surfaces (e.g., chips, sensors, nanoparticles) with carboxylic acid groups for subsequent covalent immobilization of biomolecules.
• Intermediate for Further Derivatization: The carboxylic acid group allows for easy conversion to active esters (NHS, etc.) or amides, making it a versatile building block for custom synthesis.

Basic Information

Product Name	m-Peg13-Acid
CAS No.	1239588-11-4
Molecular Formula	C28H56O15
Molecular Weight	632.74 g/mol
Synonyms	mPEG13-acid; α-Methoxy-ω-carboxy-pentaethylene glycol; Methoxy-PEG13-propionic acid; 3,6,9,12,15,18,21,24,27,30,33,36,39-Tridecaoxahenpentacontanoic acid, 41-methoxy-; mPEG13-COOH; CH3O-(CH2CH2O)13-CH2CH2COOH; PEG 600 acid, monomethyl ether; Poly(ethylene glycol) methyl ether carboxylic acid (n~13)
EINECS	Contact for details

Quality Control

Our m-Peg13-Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and biotech research. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Acid Value (Titration)	Contact for details
Water Content (KF)	≤ 1.0%
Molecular Weight (NMR)	600 - 650 g/mol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.