Description

tert-Butyl 4-(6-Chloropyridin-2-Yl)Piperazine-1-Carboxylate CAS NO 1239369-20-0 is a high-value, protected piperazine derivative featuring a chloropyridine moiety. This compound serves as a critical pharmaceutical intermediate and building block in modern organic synthesis, enabling the development of novel active ingredients. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging the chloropyridine structure.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand & Catalyst Preparation: The piperazine nitrogen atoms can be functionalized to create chelating ligands for metal catalysis.
• Custom Synthesis Projects: A starting material for contract research organizations (CROs) and CDMOs working on bespoke molecular targets.

Basic Information

Product Name	tert-Butyl 4-(6-Chloropyridin-2-Yl)Piperazine-1-Carboxylate
CAS No.	1239369-20-0
Molecular Formula	C14H20ClN3O2
Molecular Weight	297.78 g/mol
Synonyms	1-Boc-4-(6-chloropyridin-2-yl)piperazine; tert-Butyl 4-(6-chloro-2-pyridinyl)-1-piperazinecarboxylate; 4-(6-Chloropyridin-2-yl)piperazine-1-carboxylic acid tert-butyl ester; 2-(1-Boc-piperazin-4-yl)-6-chloropyridine; 6-Chloro-2-(1-Boc-piperazin-4-yl)pyridine; 1-(tert-Butoxycarbonyl)-4-(6-chloropyridin-2-yl)piperazine; Boc-4-(6-chloro-2-pyridyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(6-Chloropyridin-2-Yl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) with detailed specifications are provided for each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.