Description

2-Bromo-4-Phenyl-Nicotinic Acid Ethyl Ester is a high-value brominated nicotinate derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a versatile halogenated and esterified scaffold for constructing complex heterocyclic systems and pharmaceutical candidates. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators that require a halogenated pyridine core.
• Material Science Research: Serves as a precursor for creating functionalized organic ligands and monomers used in specialty polymers and electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological pathways and protein interactions.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis, including cross-coupling and heterocycle formation reactions.
• Custom Synthesis & Scale-Up: Starting material for contract manufacturing organizations (CMOs) engaged in producing bespoke intermediates for client projects.

Basic Information

Product Name	2-Bromo-4-Phenyl-Nicotinic Acid Ethyl Ester
CAS No.	1237962-71-8
Molecular Formula	C14H12BrNO2
Molecular Weight	306.16 g/mol
Synonyms	Ethyl 2-Bromo-4-phenylnicotinate; 2-Bromo-4-phenyl-3-pyridinecarboxylic Acid Ethyl Ester; 3-Pyridinecarboxylic acid, 2-bromo-4-phenyl-, ethyl ester; Ethyl 2-bromo-4-phenyl-3-pyridinecarboxylate; 4-Phenyl-2-bromonicotinic acid ethyl ester; 2-Bromo-4-phenylnicotinic acid ethyl ester; 1237962-71-8
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Phenyl-Nicotinic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and batch-specific Certificates of Analysis (COA) to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to minimize moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.