Description

3-(1-Amino-1-Methylethyl)-n-[(2R)-1,2,3,4-Tetrahydro-7-Oxo-1,8-Naphthryridin-4-Yl)Oxy]-2-Naphthalenyl]-5-Benzamide Dihydrochloride is a high-purity, non-racemic chiral compound designed for advanced research and development. This product is critical for pharmaceutical and biotechnology applications where precise molecular structure and high chemical purity are paramount. It serves as a key intermediate or active pharmaceutical ingredient (API) for researchers and manufacturers in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic and receptor binding assays to study biological pathways.
• Process Chemistry Development: Serves as a key material for scaling up synthetic routes and optimizing manufacturing processes under GMP conditions.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the final stages of synthesizing target drug molecules for preclinical and clinical studies.
• Chiral Catalyst or Ligand Precursor: Its defined stereochemistry makes it a valuable starting point for developing asymmetric synthesis catalysts.

Basic Information

Product Name	3-(1-Amino-1-Methylethyl)-n-[(2R)-1,2,3,4-Tetrahydro-7-Oxo-1,8-Naphthryridin-4-Yl)Oxy]-2-Naphthalenyl]-5-Benzamide Dihydrochloride
CAS No.	1237536-18-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(2R)-4-({3-[(1-Amino-1-methylethyl)carbamoyl]-2-naphthyl}oxy)-1,2,3,4-tetrahydro-7-oxo-1,8-naphthyridine-5-carboxamide dihydrochloride; 3-[(1-Amino-1-methylethyl)carbamoyl]-N-[(2R)-1,2,3,4-tetrahydro-7-oxo-1,8-naphthyridin-4-yl]oxy-2-naphthamide dihydrochloride; 5-Benzamide, 3-[(1-amino-1-methylethyl)amino]-N-[[(2R)-1,2,3,4-tetrahydro-7-oxo-1,8-naphthyridin-4-yl]oxy]-2-naphthalenyl-, dihydrochloride; CAS 1237536-18-3
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing all specifications are available upon request. We support development under quality systems suitable for cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.