Description

4-(2-Aminopropanoyl)-2-Piperazinone Hydrochloride is a high-purity pharmaceutical intermediate and building block used in advanced organic synthesis. This compound is critical for research and development in medicinal chemistry, particularly for constructing complex heterocyclic scaffolds. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Peptidomimetic Synthesis: Serves as a constrained scaffold in the design and synthesis of peptide analogs and mimetics.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and protein-protein interactions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.
• Academic Research: Employed in university and institutional labs for methodological development in heterocyclic chemistry.

Basic Information

Product Name	4-(2-Aminopropanoyl)-2-Piperazinone Hydrochloride
CAS No.	1236262-73-9
Molecular Formula	C7H14ClN3O2
Molecular Weight	207.66 g/mol
Synonyms	2-Piperazinone, 4-(2-aminopropanoyl)-, hydrochloride; 4-(2-Aminopropanoyl)piperazin-2-one hydrochloride; 4-(2-Aminopropionyl)-2-piperazinone hydrochloride; 4-(2-Aminopropanoyl)-2-piperazinone HCl; α-AMINOPROPIONYL PIPERAZINONE HYDROCHLORIDE; 1236262-73-9; 4-(2-Aminopropanoyl)piperazin-2-one HCl salt
EINECS	Contact for details

Quality Control

Our 4-(2-Aminopropanoyl)-2-Piperazinone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.