Description

1-(Piperazin-1-Yl)Prop-2-En-1-One Hydrochloride is a high-purity, functionalized piperazine derivative supplied as a hydrochloride salt. This compound serves as a critical pharmaceutical intermediate and building block in advanced organic synthesis, valued for its reactive enone moiety and the basicity of the piperazine ring. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and plant growth regulators.
• Chemical Biology & Proteomics: Acts as a versatile building block for creating chemical probes, affinity labels, and enzyme inhibitors for biological research.
• Polymer & Material Science: Employed in the synthesis of specialty polymers, coatings, and functional materials requiring piperazine-based monomers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up services.

Basic Information

Product Name	1-(Piperazin-1-Yl)Prop-2-En-1-One Hydrochloride
CAS No.	1235440-97-7
Molecular Formula	C7H13ClN2O
Molecular Weight	176.65 g/mol
Synonyms	1-(1-Piperazinyl)-2-propen-1-one hydrochloride; 1-Acryloylpiperazine hydrochloride; N-Acryloylpiperazine hydrochloride; Acryloylpiperazine HCl; 2-Propen-1-one, 1-(1-piperazinyl)-, hydrochloride; Piperazine, 1-acryloyl-, hydrochloride; 1-Piperazin-1-ylprop-2-en-1-one hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Piperazin-1-Yl)Prop-2-En-1-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.