Description

6-(Cyclobutylmethoxy)Pyridine-3-Carboxylic Acid is a high-purity pyridine derivative building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique cyclobutylmethoxy-substituted structure enables precise molecular modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting small molecule therapeutics.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and materials science applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific pyridine carboxylic acid derivatives.
• Academic & Industrial R&D: Utilized in research laboratories for exploring new chemical reactions and developing novel synthetic methodologies.

Basic Information

Product Name	6-(Cyclobutylmethoxy)Pyridine-3-Carboxylic Acid
CAS No.	1235440-26-2
Molecular Formula	C11H13NO3
Molecular Weight	207.23 g/mol
Synonyms	3-Pyridinecarboxylic acid, 6-(cyclobutylmethoxy)-; 6-(Cyclobutylmethoxy)nicotinic acid; 6-Cyclobutylmethoxynicotinic acid; 6-O-(Cyclobutylmethyl)nicotinic acid; 1235440-26-2; Nicotinic acid, 6-(cyclobutylmethoxy)-; 6-(Cyclobutylmethoxy)pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-(Cyclobutylmethoxy)Pyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards, including pharmaceutical R&D under GMP-like controls.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.