Description

tert-Butyl 3-(1-Aminoethyl)Piperidine-1-Carboxylate is a high-purity, protected piperidine derivative serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce a functionalized piperidine moiety with a protected amine group.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the construction of advanced pesticide and herbicide molecules that require specific stereochemistry for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetic Research: Employed in the design and synthesis of peptide analogs and conformationally restricted scaffolds for drug discovery.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring high chemical purity and reliable stereochemical integrity.
• Academic & Industrial R&D: Used in methodological studies and for exploring new synthetic routes to complex nitrogen-containing heterocycles.

Basic Information

Product Name	tert-Butyl 3-(1-Aminoethyl)Piperidine-1-Carboxylate
CAS No.	1235439-55-0
Molecular Formula	C12H24N2O2
Molecular Weight	228.33 g/mol
Synonyms	1-Boc-3-(1-aminoethyl)piperidine; 1-(tert-Butoxycarbonyl)-3-(1-aminoethyl)piperidine; 3-(1-Aminoethyl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 3-(1-aminoethyl)-1-piperidinecarboxylate; N-Boc-3-(1-aminoethyl)piperidine; 1-N-Boc-3-(1-aminoethyl)piperidine; 3-(1-Aminoethyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(1-Aminoethyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.