Description

tert-Butyl 3-Bromo-6-Chloropicolinate is a high-purity, multi-functional chemical intermediate essential for advanced organic synthesis. This compound is valued for its unique halogenated picolinate structure, which enables precise molecular construction in complex chemical pathways. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs) requiring high-fidelity halogenated intermediates.

Basic Information

Product Name	tert-Butyl 3-Bromo-6-Chloropicolinate
CAS No.	1235036-15-3
Molecular Formula	C10H11BrClNO2
Molecular Weight	292.56 g/mol
Synonyms	tert-Butyl 3-bromo-6-chloropyridine-2-carboxylate; 3-Bromo-6-chloropicolinic acid tert-butyl ester; 2-Pyridinecarboxylic acid, 3-bromo-6-chloro-, 1,1-dimethylethyl ester; 6-Chloro-3-bromopicolinic acid tert-butyl ester; tert-Butyl 3-bromo-6-chloro-2-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Bromo-6-Chloropicolinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container must be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.