Description

1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-bromo-, methyl ester is a high-purity brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by medicinal chemists and process development scientists in the life sciences industry for the synthesis of novel active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Agrochemical Development: Serves as a building block for novel crop protection agents and pesticides.
• Material Science: Potential monomer or precursor for functional organic materials and electronic chemicals.
• Chemical Biology: Utilized in the development of molecular probes and biochemical tools.
• Contract Research & Manufacturing (CRO/CMO): Supplied for custom synthesis and scale-up projects.

Basic Information

Product Name	1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-bromo-, methyl ester
CAS No.	1234616-83-1
Molecular Formula	C9H7BrN2O2
Molecular Weight	255.07 g/mol
Synonyms	5-Bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid methyl ester; Methyl 5-bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 5-Bromo-1H-7-azaindole-2-carboxylic acid methyl ester; 5-Bromo-7-azaindole-2-carboxylic acid methyl ester; 5-Bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylate, methyl ester; 1234616-83-1; 5-Bromo-1H-pyrrolo[2,3-b]pyridine-2-methyl carboxylate
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-bromo-, methyl ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for advanced synthetic intermediates. Certificates of Analysis (COA) with detailed HPLC, NMR, and MS data are provided to guarantee traceability and batch-to-batch reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.