Description

4-Bromo-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid is a high-value brominated heterocyclic building block essential for modern pharmaceutical and agrochemical research. This compound serves as a critical intermediate in the synthesis of complex molecules, enabling the development of novel active ingredients. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for lead optimization and the creation of new chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, anticancer agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology: Employed as a probe or linker in the design of chemical tools for studying biological pathways.
• Material Science: Potential precursor for advanced organic electronic materials and ligands in catalysis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and library production.
• Academic Research: Used in university and institutional labs for methodological development and novel heterocycle chemistry.

Basic Information

Product Name	4-Bromo-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid
CAS No.	1234616-71-7
Molecular Formula	C8H5BrN2O2
Molecular Weight	241.04 g/mol
Synonyms	4-Bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 4-Bromo-2-carboxy-1H-pyrrolo[2,3-b]pyridine; 4-Bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 4-Bromo-7-azaindole-2-carboxylic acid; 4-Bromo-2-carboxy-7-azaindole; 4-Bromo-1H-7-azaindole-2-carboxylic acid; 4-Bromo-2-(carboxy)-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 4-Bromo-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.