Description

[1,2,4]Triazolo[1,5-A]Pyridine-8-Carboxylic Acid is a high-purity heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its fused triazolopyridine core structure makes it a valuable intermediate for developing novel pharmaceuticals and agrochemicals. This compound is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and synthesis of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Material Science Precursor: Serves as a functionalized precursor for creating organic ligands in coordination chemistry and advanced polymeric materials.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a core fragment in fragment-based drug discovery.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological development and novel heterocycle synthesis.

Basic Information

Product Name	[1,2,4]Triazolo[1,5-A]Pyridine-8-Carboxylic Acid
CAS No.	1234616-36-4
Molecular Formula	C7H4N4O2
Molecular Weight	176.14 g/mol
Synonyms	8-Carboxy[1,2,4]triazolo[1,5-a]pyridine; 1,2,4-Triazolo[1,5-a]pyridine-8-carboxylic acid; Triazolopyridine-8-carboxylic acid; [1,2,4]Triazolopyridine-8-carboxylic acid; 8-([1,2,4]Triazolo[1,5-a]pyridinyl)carboxylic acid
EINECS	Contact for details

Quality Control

Our [1,2,4]Triazolo[1,5-A]Pyridine-8-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.