Description

(R)-Methyl 1-Cbz-Piperidine-3-Carboxylate is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic utility. This compound is valued for its role in constructing complex molecules, particularly in the synthesis of active pharmaceutical ingredients (APIs) and bioactive compounds. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce a stereochemically defined piperidine moiety.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Peptidomimetics & Bioactive Molecule Synthesis: Used to incorporate constrained, stereodefined amino acid analogs into peptide backbones to enhance stability and biological activity.
• Asymmetric Synthesis: Serves as a versatile starting material or chiral auxiliary in catalytic asymmetric transformations and multi-step synthetic routes.
• Agrochemical Research: Intermediate in the development of new chiral pesticides and herbicides where specific stereochemistry is crucial for efficacy.
• Academic & Process Chemistry: Employed in methodological studies, route scouting, and scale-up process development for complex organic molecules.

Basic Information

Product Name	(R)-Methyl 1-Cbz-Piperidine-3-Carboxylate
CAS No.	1234576-85-2
Molecular Formula	C15H19NO4
Molecular Weight	277.32 g/mol
Synonyms	(R)-Methyl 1-[(Benzyloxy)carbonyl]piperidine-3-carboxylate; (R)-1-Cbz-3-Piperidinecarboxylic Acid Methyl Ester; Methyl (R)-1-(Benzyloxycarbonyl)piperidine-3-carboxylate; (R)-1-N-CBZ-3-Carbomethoxypiperidine; (3R)-1-[(Phenylmethoxy)carbonyl]piperidine-3-carboxylic acid methyl ester; (R)-1-Benzyloxycarbonylpiperidine-3-carboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our (R)-Methyl 1-Cbz-Piperidine-3-Carboxylate is manufactured under strict quality systems to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive analytical data, including chiral purity verification by HPLC. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with each batch to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider holding under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.