Description

m-Peg8-Aldehyde is a heterobifunctional polyethylene glycol (PEG) derivative featuring a reactive aldehyde group at one terminus and a methoxy group at the other. This compound is essential for creating stable, hydrophilic linkers in bioconjugation and cross-linking applications, enabling the precise modification of biomolecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing drug delivery systems, diagnostic reagents, and functionalized surfaces.

Application

• Bioconjugation and Cross-linking: Used to covalently attach peptides, proteins, or antibodies to surfaces, nanoparticles, or other polymers via the reactive aldehyde group.
• Drug Delivery System Development: Serves as a key building block for synthesizing PEGylated prodrugs or creating stealth liposomes to improve pharmacokinetics and reduce immunogenicity.
• Diagnostic Reagent Preparation: Employed in the functionalization of biosensors, microarray slides, and other diagnostic platforms to immobilize capture molecules.
• Hydrogel and Biomaterial Fabrication: Acts as a cross-linker or functional component in the synthesis of hydrogels and biocompatible materials for tissue engineering.
• Surface Modification: Used to create hydrophilic, non-fouling coatings on medical devices and implants to prevent protein adsorption and bacterial adhesion.
• Antibody-Drug Conjugate (ADC) Research: Provides a versatile linker for site-specific conjugation of cytotoxic payloads to monoclonal antibodies.

Basic Information

Product Name	m-Peg8-Aldehyde
CAS No.	1234369-95-9
Molecular Formula	C19H38O10
Molecular Weight	426.5 g/mol
Synonyms	mPEG8-CHO; Methoxy-PEG8-aldehyde; α-Methoxy-ω-aldehyde-octaethylene glycol; 2,5,8,11,14,17,20,23-Octaoxapentacosan-25-al; 1-(Methoxyoctaethylene glycol)acetaldehyde; O-(2-(2-(2-(2-(2-(2-(2-(2-Methoxyethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethyl)hydroxylamine aldehyde derivative; Aldehyde-PEG8-OMe
EINECS	Contact for details

Quality Control

Our m-Peg8-Aldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and assay, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. This product is hygroscopic and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 90.0%
Water Content (KF)	≤ 1.0%
Molecular Weight Confirmation (MS)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.