Description

(2-Bromo-Pyridin-4-Yl)-Acetic Acid Methyl Ester CAS NO 1234217-58-3 is a high-purity brominated pyridine derivative, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in providing a reactive handle for cross-coupling reactions and further functionalization, enabling the efficient construction of complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries, where it is used to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the development of organic electronic materials, ligands for catalysis, and functional polymers.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Stille, and Negishi couplings to form biaryl and other complex structures.
• Chemical Biology & Proteomics: Utilized in the design and synthesis of molecular probes and activity-based protein profiling reagents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development of scalable synthetic routes.

Basic Information

Product Name	(2-Bromo-Pyridin-4-Yl)-Acetic Acid Methyl Ester
CAS No.	1234217-58-3
Molecular Formula	C8H8BrNO2
Molecular Weight	230.06 g/mol
Synonyms	Methyl (2-bromopyridin-4-yl)acetate; 4-Pyridineacetic acid, 2-bromo-, methyl ester; 2-Bromo-4-(methoxycarbonylmethyl)pyridine; (2-Bromo-4-pyridyl)acetic acid methyl ester; Methyl 2-bromo-4-pyridylacetate; 2-Bromopyridin-4-ylacetic acid methyl ester; Methyl (2-bromo-4-pyridinyl)acetate
EINECS	Contact for details

Quality Control

Our (2-Bromo-Pyridin-4-Yl)-Acetic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.