Description

5-(5-(2-(3-Aminopropoxy)-6-Methoxyphenyl)-1H-Pyrazol-3-Ylamino)Pyrazine-2-Carbonitrile Hydrochloride is a high-purity, complex heterocyclic compound supplied as a hydrochloride salt, offering enhanced stability and handling properties for advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and research chemical in the development of novel therapeutic agents, particularly in kinase inhibitor and targeted oncology research. It is essential for medicinal chemists and process development scientists in pharmaceutical R&D and fine chemical manufacturing seeking to build sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential kinase inhibitors and other targeted small-molecule drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs for novel therapeutic targets.
• Biochemical Probe Development: Serves as a core structure for creating chemical probes to study specific enzyme functions and cellular pathways.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development projects for global clients.
• Academic Research: Utilized in university and institutional labs for cutting-edge research in chemical biology and drug discovery methodologies.

Basic Information

Item	Detail
Product Name	5-(5-(2-(3-Aminopropoxy)-6-Methoxyphenyl)-1H-Pyrazol-3-Ylamino)Pyrazine-2-Carbonitrile Hydrochloride
CAS No.	1234015-54-3
Molecular Formula	C18H20N8O2 • HCl
Molecular Weight	416.86 g/mol (Free base: 380.40 g/mol)
Synonyms	5-[[5-[2-(3-Aminopropoxy)-6-methoxyphenyl]-1H-pyrazol-3-yl]amino]pyrazine-2-carbonitrile hydrochloride; 5-((5-(2-(3-Aminopropoxy)-6-methoxyphenyl)-1H-pyrazol-3-yl)amino)pyrazine-2-carbonitrile HCl; UNII-8Q3FGN8S4K; 8Q3FGN8S4K; 1234015-54-3 (parent); Pyrazinecarbonitrile, 5-[[5-[2-(3-amino-1-oxopropoxy)-6-methoxyphenyl]-1H-pyrazol-3-yl]amino]-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Every batch of 5-(5-(2-(3-Aminopropoxy)-6-Methoxyphenyl)-1H-Pyrazol-3-Ylamino)Pyrazine-2-Carbonitrile Hydrochloride is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical use. Comprehensive analytical characterization, including HPLC, NMR, and MS, is performed to confirm identity and purity. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere (e.g., nitrogen or argon) in a desiccator.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.