Description

tert-Butyl 4-(Propan-2-Ylsulfonamido)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core protected by a Boc (tert-butoxycarbonyl) group and functionalized with an isopropylsulfonamide moiety. This compound is of significant value for its role in the synthesis of complex bioactive molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, especially those targeting neurological disorders and other conditions where modulation of specific receptors is desired.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Protease Inhibitor Synthesis: Serves as a precursor in the development of protease inhibitors for various disease pathways.
• Ligand and Receptor Modulator Development: Employed in creating molecules designed to interact with specific enzymes or receptors in the central nervous system.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and chemical biology studies.

Basic Information

Product Name	tert-Butyl 4-(Propan-2-Ylsulfonamido)Piperidine-1-Carboxylate
CAS No.	1233958-40-1
Molecular Formula	C13H26N2O4S
Molecular Weight	306.42 g/mol
Synonyms	1-Boc-4-(isopropylsulfonylamino)piperidine; 1-(tert-Butoxycarbonyl)-4-[(propan-2-yl)sulfonylamino]piperidine; 4-[(Isopropylsulfonyl)amino]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-[(isopropylsulfonyl)amino]piperidine-1-carboxylate; 4-(Isopropylsulfonamido)piperidine-1-carboxylic acid tert-butyl ester; N-(1-Boc-4-piperidinyl)isopropylsulfonamide; BOC-4-(Isopropylsulfonamido)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(Propan-2-Ylsulfonamido)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided and can be tailored to meet specific client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.