Description

3-Fluoro-2-Nitro-n-(Piperidin-4-Ylmethyl)Aniline Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular scaffold combining aniline, piperidine, and nitro-fluoro substituents. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new drug candidates or optimize synthetic routes.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the piperidine moiety.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Agrochemical Development: Serves as a building block for creating novel active ingredients in crop protection research.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes under cGMP conditions.
• Academic Research: Employed in university and institutional labs for methodological development and novel heterocyclic chemistry.

Basic Information

Product Name	3-Fluoro-2-Nitro-n-(Piperidin-4-Ylmethyl)Aniline Hydrochloride
CAS No.	1233955-82-2
Molecular Formula	C13H17FN3O2 • HCl
Molecular Weight	299.75 g/mol (Free base: 263.29 g/mol)
Synonyms	N-[(4-Piperidinyl)methyl]-3-fluoro-2-nitroaniline hydrochloride; 3-Fluoro-2-nitro-N-(piperidin-4-ylmethyl)aniline HCl; 1-Piperidinemethanamine, N-(3-fluoro-2-nitrophenyl)-, hydrochloride; 3-Fluoro-2-nitroaniline, N-(4-piperidinylmethyl)-, hydrochloride; 1233955-82-2; 3-Fluoro-2-nitro-N-(piperidin-4-ylmethyl)benzenamine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Nitro-n-(Piperidin-4-Ylmethyl)Aniline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment aligns with the standards expected for pharmaceutical development, supporting your regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.